Synthesis and antimalarial activity of pyrazolo and pyrimido benzothiazine dioxide derivatives

A series of phenylsubstituted pyrazolo and pyrimido benzothiazine dioxide derivatives were synthesized and investigated for their abilities to inhibit b-hematin formation, hemoglobin hydrolysis and in vivo for their antimalarial efficacy in rodent Plasmodium berghei. Compounds 3-amino-7-chloro-9-(20...

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Veröffentlicht: 2011
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Online-Zugang:http://hdl.handle.net/10872/304
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