PINDOLOL Df,CREASES PLASMA ANGIOTENSIN-CONVERTING ENZYME ACTIVITY IN YOUNG SPONTANEOUSLY HYPERTTNSIVE RATS

The B-adrenoceptor antagonist pindolol, given p.o. (10 mg/kg, once a day for 7 days) to 4 and 24 week old male spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY), decreased plasma angiotensin-converting enzyme (ACE) activity only in young SHR. Kinetic studies indicated that the treatm...

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Publicado em: 1985
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Acesso em linha:http://hdl.handle.net/10872/171
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