Circulación hiperdinámica de pacientes cirróticos: expresión renal de los efectos del propranolol
Aim: The aim of this study was to assess the influence of Nonselective blockers (NSBB) over the systemic hemodynamics and renal function in patients with compensated and decompensated cirrhosis and ascites. Methods: We performed a prospective analysis of twenty patients, ten with cirrhosis and asc...
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2017
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| Acceso en línea: | http://hdl.handle.net/10872/16587 |
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| Sumario: | Aim: The aim of this study was to assess the influence of Nonselective blockers (NSBB) over the systemic hemodynamics and renal function in patients with compensated and decompensated cirrhosis and ascites. Methods: We performed a prospective analysis of twenty patients, ten with cirrhosis and ascites and ten with spontaneous bacterial peritonitis. A control group of ten subjects was studied too. All groups underwent measurement of blood pressure, and blood and urine tests, pre and post treatment with propranolol. Results: Significant difference (p<0.04) was observed in urinary sodium between total patients without treatment and control group. The Rate of Sodium Reabsorption was significant between compensated patients and those with SBP, (p<0.04) before treatment. Patients without SBP pre and post treatment showed also, however, there was no significant difference between patients with SPB although there was a tendency to decrease sodium excretion. Low Mean arterial pressure, factor of poor prognosis in these patients showed positive correlation with low urinary sodium excretion in Child C patients with SBP post treatment. Conclusions: Patients with liver and extensive degree of hemodynamic decompensation are susceptible of renal impairment. |
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