In Vitro Anti-Trypanosoma cruzi Activity of Dronedarone, a Novel Amiodarone Derivative with an Improved Safety Profile

Amiodarone, a commonly used antiarrhythmic, is also a potent and selective anti-Trypanosoma cruzi agent. Dronedarone is an amiodarone derivative in which the 2,5-diiodophenyl moiety of the parental drug has been replaced with an unsubstituted phe- nyl group aiming to eliminate the thyroid toxicity f...

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Bibliographic Details

Published:	2012
Subjects:	Trypanosoma cruzi Amiodarone Dronedarona anti-Trypanosoma cruzi agent parental drug Drug Administration (FDA)
Online Access:	http://hdl.handle.net/10872/4389
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