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Diuretic and Natriuretic Action of Rat Atrial Natriuretic Peptide (G33) Administered Intracerebroventricularly in Rats

BRAIN RES BULL l7(2) l4l-144, 1986.-lntracerebroventricular (lVT) administration of rat atrial peptide (6-33) (rANP) to conscious male hydrated or salt-loaded rats, resulted in significant increase in urinary volume. The diuretic effects of rANP occurred during the 3 hr period of urine collection an...

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Published: 1986
Subjects:
Arterial natriuretic peptide
Natriuresis
Diuresis
lntracerebroventricular adminislrati
Fluid homeostasis
Online Access:http://hdl.handle.net/10872/177
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bitstream.checksum.fl_str_mv cc579d33fe312cf5321bcac4f204682b
8a4605be74aa9ea9d79846c1fba20a33
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
bitstream.url.fl_str_mv https://saber.ucv.ve/jspui/bitstream/10872/177/1/Isra%2cBarb1986%20BRB%20.pdf
https://saber.ucv.ve/jspui/bitstream/10872/177/2/license.txt
dc.contributor.author.none.fl_str_mv Israel, Anita
Barbella, Yarisma
dc.creator.fl_str_mv Israel, Anita
Barbella, Yarisma
dc.date.accessioned.none.fl_str_mv 2011-06-21T15:30:18Z
dc.date.available.none.fl_str_mv 2011-06-21T15:30:18Z
dc.date.issued.none.fl_str_mv 1986-03-31
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10872/177
dc.language.iso.es_VE.fl_str_mv en
dc.publisher.es_VE.fl_str_mv Bnin Research Bulletin
dc.relation.ispartofseries.none.fl_str_mv Vol. 17;l4l-144. I986
dc.subject.es_VE.fl_str_mv Arterial natriuretic peptide
Natriuresis
Diuresis
lntracerebroventricular adminislrati
Fluid homeostasis
dc.title.es_VE.fl_str_mv Diuretic and Natriuretic Action of Rat Atrial Natriuretic Peptide (G33) Administered Intracerebroventricularly in Rats
dc.type.es_VE.fl_str_mv Article
description BRAIN RES BULL l7(2) l4l-144, 1986.-lntracerebroventricular (lVT) administration of rat atrial peptide (6-33) (rANP) to conscious male hydrated or salt-loaded rats, resulted in significant increase in urinary volume. The diuretic effects of rANP occurred during the 3 hr period of urine collection and were most effective during the first hour. Most remarkably. rANP given IVT produced a dose-related increase in urinary sodium excretion at 3 hr. With a high dose of rANP. kaliuresis was significant only at 3 hr. Our results strongly suggest that ANF may play a significant role in central regulalion of fluid homeostasis. and that its natriuretic and diuretic effects may be. at least in paft, centrally mediated
id SABERUCV_9ca3a8c850ded014e7ff00a9c3dbe4d8
language_invalid_str_mv en
network_acronym_str SABERUCV
network_name_str Repositorio Institucional de la Universidad Central de Venezuela
oai_identifier_str oai:saber.ucv.ve:10872/177
publishDate 1986
publishDateSort 1986
repository.mail.fl_str_mv sfwrussians@gmail.com
repository.name.fl_str_mv Saber UCV
repository_id_str
spelling Israel, AnitaBarbella, Yarisma2011-06-21T15:30:18Z2011-06-21T15:30:18Z1986-03-31http://hdl.handle.net/10872/177BRAIN RES BULL l7(2) l4l-144, 1986.-lntracerebroventricular (lVT) administration of rat atrial peptide (6-33) (rANP) to conscious male hydrated or salt-loaded rats, resulted in significant increase in urinary volume. The diuretic effects of rANP occurred during the 3 hr period of urine collection and were most effective during the first hour. Most remarkably. rANP given IVT produced a dose-related increase in urinary sodium excretion at 3 hr. With a high dose of rANP. kaliuresis was significant only at 3 hr. Our results strongly suggest that ANF may play a significant role in central regulalion of fluid homeostasis. and that its natriuretic and diuretic effects may be. at least in paft, centrally mediatedenBnin Research BulletinVol. 17;l4l-144. I986Arterial natriuretic peptideNatriuresisDiuresislntracerebroventricular adminislratiFluid homeostasisDiuretic and Natriuretic Action of Rat Atrial Natriuretic Peptide (G33) Administered Intracerebroventricularly in RatsArticleORIGINALIsra,Barb1986 BRB .pdfIsra,Barb1986 BRB .pdfapplication/pdf112272https://saber.ucv.ve/jspui/bitstream/10872/177/1/Isra%2cBarb1986%20BRB%20.pdfcc579d33fe312cf5321bcac4f204682bMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://saber.ucv.ve/jspui/bitstream/10872/177/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5210872/177oai:saber.ucv.ve:10872/1772018-07-27 15:20:33.822Saber UCVsfwrussians@gmail.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
spellingShingle Diuretic and Natriuretic Action of Rat Atrial Natriuretic Peptide (G33) Administered Intracerebroventricularly in Rats
Arterial natriuretic peptide
Natriuresis
Diuresis
lntracerebroventricular adminislrati
Fluid homeostasis
title Diuretic and Natriuretic Action of Rat Atrial Natriuretic Peptide (G33) Administered Intracerebroventricularly in Rats
title_full Diuretic and Natriuretic Action of Rat Atrial Natriuretic Peptide (G33) Administered Intracerebroventricularly in Rats
title_fullStr Diuretic and Natriuretic Action of Rat Atrial Natriuretic Peptide (G33) Administered Intracerebroventricularly in Rats
title_full_unstemmed Diuretic and Natriuretic Action of Rat Atrial Natriuretic Peptide (G33) Administered Intracerebroventricularly in Rats
title_short Diuretic and Natriuretic Action of Rat Atrial Natriuretic Peptide (G33) Administered Intracerebroventricularly in Rats
title_sort Diuretic and Natriuretic Action of Rat Atrial Natriuretic Peptide (G33) Administered Intracerebroventricularly in Rats
topic Arterial natriuretic peptide
Natriuresis
Diuresis
lntracerebroventricular adminislrati
Fluid homeostasis
url http://hdl.handle.net/10872/177

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