The role of alanine 163 in solute permeability of Leishmania major aquaglyceroporin LmAQP1
Leishmania major aquaglyceroporin LmAQP1 allows adventitious passage of antimonite, an activated form of the drug Pentostam, which is used as the first line treatment for leishmaniasis. The extracellular C-loop of an aquaglyceroporin confers substrate specificity. Alteration of Glu125 to serine in t...
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| Publicat: |
2011
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| Accés en línia: | http://hdl.handle.net/10872/4898 |
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