Disminución de los Requerimientos Anestésicos y Analgésicos Postoperatorios, en Pacientes Sometidos a Colecistectomía Laparoscópica: Premedicación Con Paracetamol Versus Ketorolaco Intravenoso.

To compare the effects of premedication with intravenous paracetamol versus ketorolac, in decreasing intraoperative anesthetic and postoperative opioid analgesics requirements in patients undergoing laparoscopic cholecystectomy. Method: to be determined intraoperative opioid requirements, pain and a...

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Published: 2015
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Online Access:http://hdl.handle.net/10872/18135
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Summary:To compare the effects of premedication with intravenous paracetamol versus ketorolac, in decreasing intraoperative anesthetic and postoperative opioid analgesics requirements in patients undergoing laparoscopic cholecystectomy. Method: to be determined intraoperative opioid requirements, pain and analgesic requirements in the postoperative period in 100 healthy patients undergoing laparoscopic cholecystectomy. The selection was in two groups: group 1: premedicated with paracetamol and group 2: with ketorolac, both administered intravenously 30 minutes prior to surgery. Results: There weren´t statistically significant differences between groups with respect to intraoperative remifentanil consumption (group 1: 0.0739 ± 0.016, group 2: 0.0741 ± 0.018). The number of patients in group 2 had values of VAS> 4 points (22.4%) was lower than in group 1 (28.6%), but without statistically significant difference. Of the patients who merited reinforcements postoperative opioids, most merited a single reinforcement and application of analgesics during hospitalization prevailed between 3 and 12 hours, without significant differences between groups. No adverse effects were observed in the study sample. Conclusion: Paracetamol 1g IV placed preoperatively decreased anesthetic requirements and the need for postoperative analgesics, similar to preoperative administration of ketorolac 30 mg IV.