Aziridine-2,3-dicarboxylate inhibitors targeting the major cysteine protease of Trypanosoma brucei as lead trypanocidal agents

The protozoan parasite Trypanosoma brucei causes Human African trypanosomiasis, which is fatal if left untreated. Due to the toxicity of currently used drugs and emerging drug resistance, there is an urgent need for novel therapies. The major trypanosome papain-like cysteine protease expressed by th...

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Bibliographic Details

Published:	2012
Subjects:	Aziridine-2,3-dicarboxylate inhibitors cysteine protease Trypanosoma brucei
Online Access:	http://hdl.handle.net/10872/1703
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