Evaluación de la influencia de la formulación en el FPS invitro de un protector solar
The use of sunscreen is necessary, because the body's defenses against the sun's rays are not enough to offset the amount received daily. Additionally, the ozone layer has deteriorated in recent decades, reducing its filtering efficiency, increasing the incidence of UV radiation on earth, causing da...
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2013
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| Online Access: | http://hdl.handle.net/10872/3304 |
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| Summary: | The use of sunscreen is necessary, because the body's defenses against the sun's rays are not enough to offset the amount received daily. Additionally, the ozone layer has deteriorated in recent decades, reducing its filtering efficiency, increasing the incidence of UV radiation on earth, causing damage to health in general, hence the importance of proper use of sunscreens. To evaluate the efficacy of these products, have developed several in vitro methods based on spectrophotometric measurements (290-400 nm) of sunscreen, these measurements have value as a complementary approach to SPF in vivo, for economic reasons and ethical practices; used routinely, though not as a substitute for it. The methodologies in vitro acquire an important role during the stage of product development, or in studies comparing different formulations. The objective was to evaluate the influence of various emulsifiers, polymers and silicones on the in vitro SPF sunscreen. The methodology used for the formulation of sunscreens was the method of assay and error, based on an extensive literature review. To determine the in vitro SPF was used spectrophotometric method proposed by JH Vogelman et al modified. Counts were performed taking into account the absorption spectrum UVB, using the spectrophotometer Cecil CE2041®, using as P7 formula reference standard of the Method International. According to the results, no significant differences in in vitro SPF values in the different formulations evaluated, with it being concluded that the studied ingredients (emulsifiers, polymers and silicones) have no influence on the absorbance and thus nor in the in vitro SPF of a sunscreen that contains them. |
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