Influence of CTLA-4 gene polymorphism in autoimmune and infectious diseases
Cell-mediated immunity requires costimulatory activity to initiate or inhibit antigen-specific T-cell responses. CTLA-4 is an inhibitory receptor expressed by activated and regulatory T cells. The single nucleotide polymorphism (SNP) 49 A/G of the CTLA-4 gene alters intracellular distribution of CTL...
Saved in:
| Published: |
2009
|
|---|---|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10872/4899 |
| Tags: |
No Tags, Be the first to tag this record!
|